Closed Ampoule Filler and Sealer Machine Model: LI-AFS C is uses for filling and sealing of type D pre-sterilized closed ampoules. Machine built on principle of slant travel of ampoules while filling and sealing, to take care of vide variation of ampoule neck dimensions, thicknesses of available standard ampoules.
The Filling unit built on Stainless Steel Square pipe frame and totally encompassed with Stainless Steel Coverings, in pleasing matt finish. Further, large opening available at bottom side of the machine for easy cleaning. The pendant type electrical control panel is lifted from machine for ease of operation and safety. Amoule Filling & Sealing Machine is suitable for ampoule filling in pharmaceutical, cosmetic, agriculture and chemical industries.

Closed Ampoule Filling Machine Salient Features


  • Compact GMP model.
  • Suitable for filling and sealing of type ‘D’ ampoules.
  • All contact parts made from high quality Stainless Steel 316L & other Non-contact parts made from Stainless Steel 304.
  • Minimum change over parts from 1ml to 10ml ampoule size.
  • “No Ampoule – No Filling” system.
  • Ampoule neck centering during gas flushing and filling operations.
  • Possibility of nitrogen gas flushing before, during and after filling.
  • Full accessibility allows easy maintenance.
  • Machine equipped with pre-warming station.
  • Minimum change over time, little maintenance & easy cleaning.

Closed Ampoule Filling Machine Process Operation


Pre-Sterilized D Type Ampoule tray can be directly loaded into slant hopper of the machine. The magazine type cassette delivers closed ampoules on moving eccentric ampoule rack in one/two/four/six/eight’s. Ampoule rotating lever rotate the ampoules and extreme pressure of the gas heat the ampoules. Ampoule opening process is done by the manner of pre-heating and opening with the pressure of the gas (LPG + oxygen). During the stoppage of rack sequentially ampoule opening, pre-gassing, filling, post gassing, pre-heating and final sealing is achieved. Filled & sealed ampoules are collected automatically in SS tray in upright position without hand touch.

Technical Specification of Closed Ampoule Filling Machine


Model LI-AFS 1C LI-AFS 2C LI-AFS 4C
No. of Head Single Two       Four
Direction of Movement Left to Right Left to Right Left to Right
Ampoule Handling Range 1 ml to 10 ml 1 ml to 20 ml 1 ml to 5 ml
Production Output 15 to 30 ampoules/minute 30 to 55 ampoules/minute 55 to 100 ampoules/minute
Filling Accuracy ± 1% ± 1% ± 1%
Require Gas for Sealing LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Pressure Required 1 Kg. /cm2 1 Kg. /cm2 1 Kg. /cm2
Oxygen Pressure Required 1 Kg. /cm2 1 Kg. /cm2 1 Kg. /cm2
LPG Pressure Required 0.5 Kg. /cm2 0.5 Kg. /cm2 0.5 Kg. /cm2
Power Specification 0.5 H. P 1 H.P. 1 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 915mm (L) x
610mm (W) x
965mm (H)
915mm (L) x
760mm (W) x
965mm (H)
1200mm (L) x
1070mm (W) x
965mm (H)
* Specification can be changed as per customers’ requirements